Genetic alterations in pancreatic cancer

查看全文 作　　者：Muhammad Wasif [1]Saif;Lena [2]Karapanagiotou;Kostas [1]Syrigos

机构地区：[1]Yale University School of Medicine, Section of Medical Oncology, 333 Cedar Street, NewHaven, CT 06520-8032, United States;[2]Oncology Unit, Third Department of Medicine,Athens Medical School,Sotiria General Hospital,Mesogion 152, 11526 Athens,Greece

出　　处：《World Journal of Gastroenterology》索引2007年第13卷第33期,共8页

摘　　要：The diagnosis of pancreatic cancer is devastating for patients and their relatives as the incidence rate is approximately the same as mortality rate. Only a small percentage, which ranges from 0.4% to 4% of patients who have been given this diagnosis, will be alive at five years. At the time of diagnosis, 80% of pancreatic cancer patients have unresectable or metastatic disease. Moreover, the therapeutic alternatives offered by chemotherapy or radiotherapy are few, if not zero. For all these reasons, there is an imperative need of analyzing and understanding the primitive lesions that lead to invasive pancreatic adenocarcinoma. Molecular pathology of these lesions is the key of our understanding of the mechanisms underlying the development of this cancer and will probably help us in earlier diagnosis and better therapeutic results. This review focuses on medical research on pancreatic cancer models and the underlying genetic alterations. 关键词：胰腺癌端粒末端转移酶致癌基因表皮生长因素

相关文献

参考文献（67）
引证文献（10）
耦合文献（0）

参考文献(67)

引证文献(10)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Genetic alterations in pancreatic cancer

参考文献(67)

引证文献(10)

用户提示