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Moving forward in colorectal cancer research, what proteomics has to tell

查看全文 作  者:Nerea [1]Bitarte;Eva [1]Bandrés;Ruth [1]Zárate;Natalia [1]Ramirez;Jesus Garcia-[1]Foncillas 高影响力作者 机构地区:[1]Laboratory of Pharmacogenomics, Center for Medical Applied Research, Unit of Clinical Genetics, University Clinic, Department of Oncology and Radiotherapy, University Clinic, University of Navarra, Pamplona 31008, Spain高影响力机构 出  处:《World Journal of Gastroenterology》索引2007年第13卷第44期,共9页高影响力期刊 摘  要:Colorectal cancer is the third most common cancer and is highly fatal. During the last several years, research has been primarily based on the study of expression profiles using microarray technology. But now, investigators are putting into practice proteomic analyses of cancer tissues and cells to identify new diagnostic or therapeutic biomarkers for this cancer. Because the proteome reflects the state of a cell, tissue or organism more accurately, much is expected from proteomics to yield better tumor markers for disease diagnosis and therapy monitoring. This review summarizes the most relevant applications of proteomics the biomarker discovery for colorectal cancer. 关 键 词:结肠癌 高致命性 癌细胞 治疗方法
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