A combination therapy of ethanol injection and radiofrequency ablation under general anesthesia for the treatment of hepatocellular carcinoma

查看全文 作　　者：Kazutaka [1]Kurokohchi;Seishiro [1]Watanabe;Hirohito [1]Yoneyama;Akihiro [1]Deguchi;Tsutomu [1]Masaki;Takashi [1]Himoto;Hisaaki [1]Miyoshi;Hamdy Saad [1]Mohammad;Akira [2]Kitanaka;Tomohiko [2]Taminato;Shigeki [1]Kuriyama

机构地区：[1]Department of Gastroenterology and Neurology, Kagawa University School of Medicine, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan;[2]Department of Laboratory Medicine, Kagawa University School of Medicine, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan

出　　处：《World Journal of Gastroenterology》索引2008年第14卷第13期,共7页

摘　　要：AIM: To summarize the effects of laparoscopic ethanol injection and radiofrequency ablation (L-EI-RFA), thora- coscopic (T-EI-RFA) and open-surgery assisted EI-RFA (O-EI-RFA) under general anesthesia for the treatment of hepatocellular carcinoma (HCC). METHODS: Time-lag performance of RFA after ethanol injection (Time-lag PEI-RFA) was performed in all cases. The volume of coagulated necrosis and the applied en- ergy for total and per unit volume coagulated necrosis were examined in the groups treated under general (group G) or local anesthesia (group L). RESULTS: The results showed that the total applied energy and the applied energy per unit volume of whole and marginal, coagulated necrosis were significantly larger in group G than those in the group L, resulting in a larger volume of coagulated necrosis in the group G. The rate of local tumor recurrence within one year was extremely low in group G. CONCLUSION: These results suggest that EI-RFA, un- der general anesthesia, may be effective for the treat- ment of HCC because a larger quantity of ethanol and energy could be applied during treatment under pain- free condition for the patients. 关键词：肝细胞癌联合治疗乙醇注射射频切除术麻醉方法

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A combination therapy of ethanol injection and radiofrequency ablation under general anesthesia for the treatment of hepatocellular carcinoma

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