Inflammatory reaction versus endogenous peroxisome proliferator- activated receptors expression, re-exploring secondary organ complications of spontaneously hypertensive rats

查看全文 作　　者：SUN [1,2]Li;KE [3]Yan;ZHU Chun-[1]yun;TANG [1]Ning;TIAN Deng-[1]ke;GAO Yue-[1]hong;ZHENG Jian-[1]pu;BIAN [3,4]Ka 机构地区：[1]Murad Research Institute for Modernized Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;[2]Tianjin Medical University General Hospital, Tianjin 300052, China;[3]Division of Nitric Oxide and Inflammatory Medicine, E-Institute of Shanghai Universities, Shanghai 201203, China;[4]Department of Integrative Biology and Pharmacology, Institute of Molecular Medicine, University of Texas Medical School, 6431 Fannin, Houston, TX 77030, USA 出　　处：《Chinese Medical Journal》索引2008年第22期,共7页 基　　金：This work was supported by grants from E-Institutes for Nitric Oxide and Inflammatory Medicine of Shanghai Universities (No. E-04010); Key Project of Shanghai Committee of Science & Technology (No. 05JC14056); Key Project of Shanghai Municipal Education Commission (No. 05ZZ11); National Natural Science Foundation of China (No. 30500169). 摘　　要：在高血压的脉管的墙中的长期的病理学的变化可以施加的背景多重机关 systems.Accumulating 证据上的破坏效果显示煽动性的反应涉及 hypertension.Three peroxisome 的病理学的变化 激活proliferator 的受体( PPAR )被识别了: PPAR ,PPAR/,和 PPAR ,所有哪个有多重生物效果,特别这研究的 inflammation.The 目的抑制是评估 PPAR isoforms 关 键 词：高血压 过氧物酶体 受体 治疗 患者