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Genetic mechanisms underlying the pathogenesis of tropical calcific pancreatitis

查看全文 作  者:Swapna [1,2]Mahurkar;D Nageshwar [1]Reddy;G Venkat [1]Rao;Giriraj Ratan [2]Chandak 高影响力作者 机构地区:[1]Asian Institute of Gastroenterology,6-3-661,Somajiguda,Hyderabad 500082,India;[2]Genome Research Group,Centre for Cellular and Molecular Biology,Uppal Road,Hyderabad 500007,India高影响力机构 出  处:《World Journal of Gastroenterology》索引2009年第15卷第3期,共6页高影响力期刊 摘  要:Chronic pancreatitis is known to be a heterogeneous disease with varied etiologies.Tropical calcific pancreatitis(TCP) is a severe form of chronic pancreatitis unique to developing countries.With growing evidence of genetic factors contributing to the pathogenesis of TCP,this review is aimed at compiling the available information in this field.We also propose a two hit model to explain the sequence of events in the pathogenesis of TCP. 关 键 词:慢性胰腺炎 钙化胰腺炎 胰腺糖尿病 综合疾病
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