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Drug-induced liver injury due to “natural products” used for weight loss:A case report

查看全文 作  者:Giovanni [1]Tarantino;Martina Gilda [2]Pezzullo;Matteo Nicola Dario di [1]Minno;Francesco [3]Milone;Luigi Sossio [2]Pezzullo;Marco [3]Milone;Domenico [4]Capone 高影响力作者 机构地区:[1]Department of Clinical & Experimental Medicine,Federico II University Medical School,Via S.Pansini,5 80131 Naples,Italy;[2]Department of General Surgery,Federico II University Medical School,5 80131 Naples,Italy;[3]Department of Neuroscience,Section of Clinical Pharmacology,Federico II University Medical School,5 80131 Naples,Italy;[4]Department of General Surgery,ASL BN1 of Benevento,5 80131 Naples,Italy高影响力机构 出  处:《World Journal of Gastroenterology》索引2009年第15卷第19期,共4页高影响力期刊 摘  要:Taking herbal-extracts to lose weight is an underestimated health hazard.Often,these products contain active agents that can cause acute liver damage.In this case report,a 22-year-old female patient,who presented with a feature of cholestatic syndrome,was so sure that the 'natural products' were not dangerous that she did not inform her physicians that she had taken them,making their task that much more challenging.Clinical presentation mimicked acute cholecystitis and the patient underwent a cholecystectomy.Surgery was without any consequences and complications,although it did not completely cure the illness.She later admitted to having taken herbal remedies and this led to the correct diagnosis of phytotherapy-related hepatotoxicity and a successful therapeutic approach.The true incidence of phytotherapy-related hepatotoxicity and its pathogenic mechanisms are largely unknown.It is important to increase the awareness of both clinicians and patients about the potential dangers of herbal remedies. 关 键 词:药物性肝损害 天然产品 病例报告 减肥 中草药提取物 胆汁淤积综合征 植物疗法 急性肝损伤
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