前列腺癌患者血清白细胞介素-18和VEGF相关性(英文)

查看全文 作　　者：Shaojun Nong Yueping Zhang Shujun Zhou Wenguang Li Limin Ma You [1]Wu

机构地区：[1]Department of Urological Surgery, The Affiliated Hospital of Nantong University, Nantong 226001, China

出　　处：《The Chinese-German Journal of Clinical Oncology》索引2010年第9卷第11期,共5页

摘　　要：Objective: The aim of our study was to analyze interleukin-18 (IL-18) and vascular endothelial growth factor (VEGF) serum levels in patients with prostate cancer before and after operation and the possible correlation between IL-18 and VEGF serum levels. Methods: Serum IL-18 and VEGF levels were measured by enzyme-linked immunosorbent assay (ELISA) in 36 patients with prostate cancer before and after radical prostatectomy and in 25 healthy controls. Results: Serum IL-18 and VEGF levels were significantly higher in patients with prostate cancer before operation with respect to healthy controls (P < 0.05), with a highly significant correlation between IL-18 and VEGF (R = 0.800, P = 0.017). It was significantly reduced in IL-18 and VEGF after operation. IL-18 and VEGF serum concentrations were correlated with the clinicalopathological status of patients with prostate cancer. Conclusion: It is correlative with serum IL-18 and VEGF. Serum IL-18 and VEGF levels may be useful prognostic marker in patients with prostate cancer. 关键词：血清浓度前列腺癌 VEGF 血管内皮生长因子患者酶联免疫吸附试验水 ELISA

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前列腺癌患者血清白细胞介素-18和VEGF相关性(英文)

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