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Advances of Bioinformatics Tools Applied in Virus Epitopes Prediction

查看全文 作  者:Simon [1]Rayner 高影响力作者 机构地区:[1]State Key Laboratory of Virology,Wuhan Institute of Virology,Chinese Academy of Sciences高影响力机构 出  处:《Virologica Sinica》索引2011年第26卷第1期,共7页高影响力期刊 基  金:The National Natural Science Foundations of China (30870131);the National Key Projects in the Infectious Fields (2008ZX10002-011, 2008ZX10004-004) 摘  要:In recent years,the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein,a general overview of different tools currently available,including T cell and B cell epitopes prediction tools,is presented. And the principles of different prediction algorithms are reviewed briefly. Finally,several examples are present to illustrate the application of the prediction tools. 关 键 词:预测工具 表位预测 病毒抗原 生物信息学 应用 B细胞表位 预测算法 T细胞
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