Analysis of the delayed approach to the management of infected pancreatic necrosis

查看全文 作　　者：Nilesh [1]Doctor;Sujith [1]Philip;Vidhyachandra [1]Gandhi;Maharra [2]Hussain;Savio G [3]Barreto

机构地区：[1]Department of Gastrointestinal Surgery,Jaslok Hospital and Research Center;[2]Department of Surgery,Bhatia Hospital;[3]Department of General and Digestive Surgery,Flinders Medical Center

出　　处：《World Journal of Gastroenterology》索引2011年第17卷第3期,共6页

摘　　要：AIM: To analyze outcomes of delayed single-stage necrosectomy after early conservative management of patients with infected pancreatic necrosis (IPN) associated with severe acute pancreatitis (SAP). METHODS: Between January 1998 and December 2009, data from patients with SAP who developed IPN and were managed by pancreatic necrosectomy were analyzed. RESULTS: Fifty-nine of 61 pancreatic necrosectomies were performed by open surgery and 2 laparoscopically. In 55 patients, single-stage necrosectomy could be performed (90.2%). Patients underwent surgery at a median of 29 d (range 13-46 d) after diagnosis of acute pancreatitis. Sepsis and multiple organ failure accounted for the 9.8% mortality rate. Pancreatic fistulae (50.8%) predominantly accounted for the morbidity. The median hospital stay was 23 d, and the median interval for return to regular activities was 110 d.CONCLUSION: This series supports the concept of delayed single-stage open pancreatic necrosectomy for IPN. Advances in critical care, antibiotics and interventional radiology have played complementary role in improving the outcomes. 关键词：重症急性胰腺炎管理延迟感染坏死时间间隔介入放射学 IPN

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Analysis of the delayed approach to the management of infected pancreatic necrosis

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