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Recent progress in the application of microfluidic systems and gold nanoparticles in immunoassays

查看全文 作  者:CHEN [1,2]WenWen;LI [1,3]TangSong;HE [1,4]Sha;LIU [1,2]DingBin;WANG [1]Zhuo;ZHANG [1]Wei;JIANG [1]XingYu 高影响力作者 机构地区:[1]CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China;[2]Graduate Schoold of the Chinese Academy of Sctences, Beijing 100049, China;[3]Key Laboratory of Microsystems and Microstructures Manufacturing, Ministry of Education; Harbin Institute of Technology, Harbin 150080, China;[4]College of Bioengineering, Chongqing University, Chongqing 400044, China高影响力机构 出  处:《Science China Chemistry》索引2011年第54卷第8期,共6页高影响力期刊 基  金:supported by the National Natural Science Foundation of China (90813032, 20890020 & 21025520);the Ministry of Science and Technology (2009CB930000 & 2011CB933201);the Ministry of Health (2008ZX10001-010);Chinese Academy of Sciences (KJCX2-YW-M15);the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry 摘  要:Immunoassays are useful for many bioassays. Many new techniques and materials are introduced into the immunoassay to improve the efficiency. This paper reviews recent progress in the application of microfluidic systems and gold nanoparticles in immunoassay. The micro/nano technologies and materials can offer good sensitivity, fast detection, cost-effectiveness and easy signal readout. In particular, the miniaturization of microfluidics and colorimetric assays based on gold nanoparticles have dramatically improved the efficiency of immunoassays. 关 键 词:金纳米粒子 微流体系统 免疫分析 应用 微米/纳米技术 生物测定 免疫证明 成本效益
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