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Comparative Study of Antimicrobial Activity and Phytochemical Analysis of Methanolic and Aqueous Extracts of the Fruit of Emblica Officinalis against Pathogenic Bacteria

查看全文 作　　者：Avneesh [1]Kumar;Bilal Ahmd [2]Tantry;Shiak [3]Rahiman;Upasna [1]Gupta 高影响力作者 机构地区：[1]Institute of Applied Medicines & Research,Ghaziabad,Uttar Pradesh,India;[2]Department of Microbiology,College of Medicine,Al Jouf University,Saudi Arabia;[3]Department of Biochemistry,College of Medicine,Al Jouf University,Saudi Arabia高影响力机构 出　　处：《Journal of Traditional Chinese Medicine》索引2011年第31卷第3期,共5页高影响力期刊 摘　　要：Objective:To investigate antimicrobial potential of aqueous(infusions,decoctions) and methanlic extracts(1:2 and 1:5 concentrations) of Emblica officinalis(amla) against seven pathogenic bacteria namely Staphylococcs aureus,Staphylococcus saprophyticus,Escherichia coli,Enterococcus faecalis,Enterococcus cloacae,Proteus vulgaris and Klebsiella pneumoniae.Methods:The well diffusion technique was employed.The minimum inhibitory concentration(MIC) was determined using micro-broth dilution methods and phytochemical screening was done as per standard procedures.Results:Aqueous infusion extract of amla exhibited potent antimicrobial activity against E.cloacae followed by E.coli.Preliminary phytochemical analysis of E.officinalis aqueous extracts(infusions and decoctions) only showed presence of tannins,saponins,flavanoids,Terpenoids and phenols.MIC of aqueous extract of E.officinalis was most active against K.pneumoniae.Whereas MIC of methanol extract of E.officinalis shows maximum activity against E.coli.Conclusion:Emblica officinalis definitely possesses potent antimicrobial activities and this can serve as an important platform for the development of inexpensive,safe and effective 关 键 词：厚朴提取物 化学成分分析 甲醇提取物 水提取物 抗菌活性 余甘 金黄色葡萄球菌 病原菌
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