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Practical approaches to effective management of intestinal radiation injury:Benefit of resectional surgery

查看全文 作  者:Nikolaos [1]Perrakis;Evangelos [2]Athanassiou;Dimitra [3]Vamvakopoulou;Maria [1]Kyriazi;Haris [1]Kappos;Nikolaos C [3]Vamvakopoulos;Iakovos [1]Nomikos 高影响力作者 机构地区:[1]Department of Surgery,Metaxa Cancer Memorial Hospital,Piraeus 11522,Greece;[2]Department of Surgery,University of Thessalia Medical School,Larissa 41110,Greece;[3]Department of Biology and Genetics,University of Thessalia Medical School,Larissa 41110,Greece高影响力机构 出  处:《World Journal of Gastroenterology》索引2011年第17卷第35期,共4页高影响力期刊 基  金:Supported by The University Hospital of Larissa 摘  要:AIM:To study the outcome of patients undergoing surgical resection of the bowel for sustained radiation-induced damage intractable to conservative management.METHODS:During a 7-year period we operated on 17 cases (5 male,12 female) admitted to our surgical department with intestinal radiation injury (IRI).They were originally treated for a pelvic malignancy by surgical resection followed by postoperative radiotherapy.During follow-up,they developed radiation enteritis requiring surgical treatment due to failure of conservative management.RESULTS:IRI was located in the terminal ileum in 12 patients,in the rectum in 2 patients,in the descending colon in 2 patients,and in the cecum in one patient.All patients had resection of the affected region(s).There were no postoperative deaths,while 3 cases presented with postoperative complications (17.7%).All patients remained free of symptoms without evidence of recurrence of IRI for a median follow-up period of 42 mo (range,6-96 mo).CONCLUSION:We report a favorable outcome without IRI recurrence of 17 patients treated by resection of the diseased bowel segment. 关 键 词:辐射损伤 有效管理 手术切除 肠道 效益 手术治疗 IRI 恶性肿瘤
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