Overexpression of P-glycoprotein in hepatocellular carcinoma and its clinical implication

查看全文 作　　者：Kong [1]XB;Yang [1]ZK;Liang [2]LJ;Huang [2]JF;Lin [3]HL

机构地区：[1]Department of Surgery,The First Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400016,China;[2]Division of Hepatobiliary Surgery,The First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,Guangzhou 510080,Guangdong Province,China;[3]Departrnent of Pathology,Sun Yat-Sen University of Medical Sciences,Guangzhou 510089,Guangdong Province,China

出　　处：《World Journal of Gastroenterology》索引2000年第6卷第1期,共2页

基　　金：the China Medical Board of New York,Inc.,USA,Grant No.90-534 摘　　要：INTRODUCTIONMost advanced hepatocellular garcinoma (HCC) isinsensitive to most anticancer drugs which might berelated to the high frequency of expression of themultidrug resistance-1(MDR1) gene and itsproduct,P-glycoprotein (p-gp).p-gp expressionmay also be concerned with tumor progression anddifferentiation.In the present study。 关键词：Subject headings liver NEOPLASMS carcinoma HEPATOCELLULAR P-GLYCOPROTEIN MULTIDRUG resistance-1 gene IMMUNOHISTOCHEMISTRY

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Overexpression of P-glycoprotein in hepatocellular carcinoma and its clinical implication

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