Synthesis of 2-Fluoroalkylated Tetrahydrofuran Derivatives from Ethyl α-Fluoroalkylacetates

查看全文 作　　者：Bing Hao LUO;Hui Ping GUAN;Quan Fu WANG;Chang Ming HU(354 Fenglin Road. Shanghai Institute of Organic Chemistry. Chinese Academy of Sciences. Shanghai200032) 出　　处：《Chinese Chemical Letters》索引1997年第8卷第7期,共4页 摘　　要：Ethyl α-(2-alkenyl)-α-perfiuoroacylacetates (4) are synthesized from the reaction of ethyl αperfiuoroalkylacetates with allylic alcohols in the presence of the mixed base of triethylamine and sodium dicarbonate. Iodoenoletherification of the compounds 4 afforded 2-fluoroalkylated tetrahydrofuran derivatives 5 under the improved conditions. The possible reaction pathwaays are suggested. 关 键 词：Fluoroalkylacetates