CD133 and membrane microdomains:Old facets for future hypotheses

查看全文 作　　者：Christine A [1]Fargeas;Jana [1]Karbanová;József [1]Jászai;Denis [1]Corbeil

机构地区：[1]Tissue Engineering Laboratories (BIOTEC),Technische Universitt Dresden,D-01307 Dresden,Germany

出　　处：《World Journal of Gastroenterology》索引2011年第17卷第36期,共4页

基　　金：Supported by Deutsche Forschungsgemeinschaft(TRR83 No.6;SFB655 B3;CO298/5-1) 摘　　要：Understanding all facets of membrane microdomains in normal and cancerous cells within the digestive tract is highly important,not only from a clinical point of view,but also in terms of our basic knowledge of cellular transformation.By studying the normal and cancer stem cell-associated molecule CD133 (prominin-1),novel aspects of the organization and dynamics of polarized epithelial cells have been revealed during the last decade.Its association with particular membrane microdomains is highly relevant in these contexts and might also offer new avenues in diagnosis and/or targeting of cancer stem cells. 关键词：细胞膜微区正常细胞细胞转化上皮细胞干细胞消化道癌症

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CD133 and membrane microdomains:Old facets for future hypotheses

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