Cerebrovascular hemodynamics in patients with cerebral arteriosclerosis

查看全文 作　　者：Jianbo [1]Yang;Changcong [2]Cui;Chengbin [1]Wu

机构地区：[1]Department of Neurology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China;[2]Department of Cardiology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China

出　　处：《Neural Regeneration Research》索引2011年第6卷第32期,共5页

基　　金：the Technology Research Program of Shaanxi Province, No. 2009K18-02 摘　　要：The present study observed hemodynamic changes in 26 patients with cerebral arteriosclerosis using a cerebral circulation dynamics detector and transcranial Doppler. In patients with cerebral arteriosclerosis the blood supply and flow rate in the bilateral carotid arteries and the blood flow rate in the anterior cerebral and middle cerebral arteries were similar to normal controls, but the cerebral vascular resistance, critical pressure and pulsatility index were increased, and cerebral arterial elasticity and cerebral blood flow autoregulation were decreased. Compared with the le-sioned hemisphere of patients with cerebral infarction, the total blood supply and blood flow rate of patients with cerebral arteriosclerosis were higher. Compared with normal subjects, patients with cerebral arteriosclerosis exhibited cognitive disturbances, mainly in short-term memory, attention, abstract capability, and spatial and executive dysfunction. Results showed that cerebral arteriosclerosis does not directly affect the blood supply of a cerebral hemisphere, but affects cognitive function. The increased cerebral vascular resistance and reduced autoregulation of cerebral blood vessels may be important hemodynamic mechanisms of arteriosclerosis-induced cerebral infarction. 关键词：血流动力学动脉硬化脑动脉患者认知功能障碍血液供应血流速度自动调节

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Cerebrovascular hemodynamics in patients with cerebral arteriosclerosis

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