Review of dynamic contrast-enhanced ultrasound guidance in ablation therapy for hepatocellular carcinoma

查看全文 作　　者：Yasunori [1]Minami;Masatoshi [1]Kudo

机构地区：[1]Department of Gastroen-terology and Hepatology, Kinki University School of Medicine

出　　处：《World Journal of Gastroenterology》索引2011年第17卷第45期,共8页

摘　　要：Local ablative techniques-percutaneous ethanol injection, microwave coagulation therapy and radiofrequency ablation (RFA)-have been developed to treat unresectable hepatocellular carcinoma (HCC). The success rate of percutaneous ablation therapy for HCC depends on correct targeting of the tumor via an imaging technique. However, probe insertion often is not completely accurate for small HCC nodules, which are poorly def ined on conventional B-mode ultrasound (US) alone. Thus, multiple sessions of ablation therapy are frequently required in diffi cult cases. By means of two breakthroughs in US technology, harmonic imaging and the development of second-generation contrast agents, dynamic contrast-enhanced harmonic US imaging with an intravenous contrast agent can depict tumor vascularity sensitively and accurately, and is able to evaluate small hypervascular HCCs even when B-mode US cannot adequately characterize the tumors. Therefore, dynamic contrast-enhanced US can facilitate RFA electrode placement in hypervascular HCC, which is poorly depicted by B-mode US. The use of dynamic contrast-enhanced US guidance in ablation therapy for liver cancer is an effi cient approach. Here, we present an overview of the current status of dynamic contrast-enhanced US-guided ablation therapy, and summarize the current indications and outcomes of reported clinical use in comparison with that of other modalities. 关键词：B型超声治疗肝癌引导成像技术射频消融静脉注射对比度增强

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Review of dynamic contrast-enhanced ultrasound guidance in ablation therapy for hepatocellular carcinoma

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