Effects of rare earth elements La and Yb on the morphological and functional development of zebrafish embryos

查看全文 作　　者：Jun'an [1,2]Cui;Zhiyong [1]Zhang;Wei [1]Bai;Ligang [2]Zhang;Xiao [1]He;Yuhui [1]Ma;Yan [2]Liu;Zhifang [1]Chai

机构地区：[1]Key Laboratory of Nuclear Analytical Techniques, and Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, the Chinese Academy of Sciences, Beijing 100049, China;[2]Qingdao University of Science and Technology, College of Environment and Safety Engineering, Qingdao 266042, China

出　　处：《Journal of Environmental Sciences》索引2012年第24卷第2期,共5页

基　　金：supported by the National Natural Science Foundation of China (No. 10875136,10905062,11005118);the Ministry of Science and Technology of China (No. 2011CB933400) 摘　　要：In recent years,with the wide applications and mineral exploitation of rare earth elements,their potential environmental and health effects have caused increasing public concern.Effect of rare earth elements La and Yb on the morphological and functional development of zebrafish embryos were studied.The embryos were exposed to La3+ or Yb3+ at 0,0.01,0.1,0.3,0.5 and 1.0 mmol/L,respectively.Early life stage parameters such as egg and embryo mortality,gastrula development,tail detachment,eyes,somite formation,circulatory system,pigmentation,malformations,hatching rate,length of larvae and mortality were investigated.The results showed La3+ and Yb3+ delayed zebrafish embryo and larval development,decreased survival and hatching rates,and caused tail malformation in a concentration-dependent way.Moreover,heavy rare-earth ytterbium led to more severe acute toxicity of zebrafish embryo than light rare-earth lanthanum. 关键词：稀土元素斑马鱼胚胎功能开发形态 YB LA 幼虫发育

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Effects of rare earth elements La and Yb on the morphological and functional development of zebrafish embryos

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