Botulinum toxin injection improved voluntary motor control in selected patients with post-stroke spasticity

查看全文 作　　者：Shuo-Hsiu [1,2]Chang;Gerald E [1,2]Francisco;Sheng [1,2]Li

机构地区：[1]UT Health Motor Recovery Laboratory at the Institute for Rehabilitation and Research (TIRR), Memorial Hermann Hospital, Houston 77030 Texas, USA;[2]Department of Physical Medicine and Rehabilitation, University of Texas Health Science Center at Houston, Houston 77030, Texas, USA

出　　处：《Neural Regeneration Research》索引2012年第7卷第18期,共4页

基　　金：supported in part by NIH grants(NIH/NINDS R01NS060774;NIH/NICHD/NCMRR R24 HD050821-08)under subcontract with the Rehabilitation Insti-tute of Chicago 摘　　要：The effect of botulinum toxin type A injection on voluntary grip control was examined in a 53-year-old female, who sustained a hemorrhagic right middle cerebral artery stroke 3 years previously, which resulted in finger flexor spasticity and residual weak finger/wrist extension. The patient received 50 units of botulinum toxin type A injection each to the motor points (2 sites/muscle) of the left flexor digitorum superficialis and flexor digitorum profundus, respectively. Botulinum toxin injection led to weakness and tone reduction in the spastic finger flexors, but improved grip release time in grip initiation/release reaction time tasks. Improved release time was accompanied by shortened extensor electromyography activity, and improved release time likely correlated with blocked co-contraction of finger flexors during voluntary finger extension. This case report demonstrated that botulinum toxin injection improved voluntary motor control of the hand in a chronic stroke patient with residual finger extension. 关键词：A型肉毒毒素电机控制肌痉挛注射患者中风发布时间反应时间

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Botulinum toxin injection improved voluntary motor control in selected patients with post-stroke spasticity

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