Current therapeutic strategies for inflammation following traumatic spinal cord injury

查看全文 作　　者：Priyanka [1,2]L.Singh;Nitin [1,2]Agarwal;James [1]C.Barrese;Robert [1,2]F.Heary

机构地区：[1]Department of Neurological Surgery,UMDNJ-New Jersey Medical School,Newark,NJ 07101-1709,USA;[2]Reynolds Family Spine Laboratory,Newark,NJ 07101-1709,USA

出　　处：《Neural Regeneration Research》索引2012年第7卷第23期,共10页

摘　　要：Damage from spinal cord injury occurs in two phases-the trauma of the initial mechanical insult and a secondary injury to nervous tissue spared by the primary insult.Apart from damage sustained as a result of direct trauma to the spinal cord,the post-traumatic inflammatory response contributes significantly to functional motor deficits exacerbated by the secondary injury.Attenuating the detrimental aspects of the inflammatory response is a promising strategy to potentially ameliorate the secondary injury,and promote significant functional recovery.This review details how the inflammatory component of secondary injury to the spinal cord can be treated currently and in the foreseeable future. 关键词：脊髓损伤炎症反应治疗外伤性继发性神经组织功能障碍功能恢复

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Current therapeutic strategies for inflammation following traumatic spinal cord injury

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