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Radical treatment of stage Ⅳ pancreatic cancer by the combination of cryosurgery and iodine-125 seed implantation

查看全文 作  者:Ji-Bing [1]Chen;Jia-Liang [1]Li;Li-Hua [2]He;Wei-Qun [1]Liu;Fei [1]Yao;Jian-Ying [1]Zeng;Yi [2]Zhang;Ke-Qiang [3]Xu;Li-Zhi [3]Niu;Jian-Sheng [3]Zuo;Ke-Cheng [3]Xu 高影响力作者 机构地区:[1]Central Lab of Guangzhou Fuda Cancer Hospital;[2]Medical Information Department of Guangzhou Fuda Cancer Hospital;[3]Cryosurgery Institute of Guangzhou Fuda Cancer Hospital高影响力机构 出  处:《World Journal of Gastroenterology》索引2012年第18卷第47期,共7页高影响力期刊 基  金:Supported by The Hai Zhu District Scientific and Technologica Plan,No.2010-Y-27;'Comprehensive Research of Pancreati Cancer Cryotherapy',Guangzhou,China 摘  要:AIM:To investigate the therapeutic effect of radical treatment and palliative treatment in stage Ⅳ pancreatic cancer patients.METHODS:81 patients were enrolled in the study.Radical treatment was performed on 51 patients,while 30 patients were put under palliative treatment.The procedural safety and interval survival for stage Ⅳ pancreatic cancer(IS-Ⅳ) was assessed by almost 2.5 years of follow-ups.The IS-Ⅳ of patients under the two kinds of treatment,and the effects of treatment timing and frequency on IS-Ⅳ,were compared.RESULTS:The IS-Ⅳ of patients who received radical treatment was significantly longer than those who received palliative treatment(P < 0.001).The IS-Ⅳ of patients who received delayed radical or palliative treatment was longer than those who received accordingly timely treatment(P = 0.0034 and 0.0415,respectively).Multiple treatments can play an important role in improving the IS-Ⅳ of patients who received radical treatment(P = 0.0389),but not for those who received palliative treatment(P = 0.99).CONCLUSION:The effect of radical treatment was significantly more obvious than that of palliative treatment,and multiple radical treatments may contribute more to patients than a single radical treatment. 关 键 词:治疗效果 胰腺癌 植入 种子 冷冻 患者 存活期
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