Deep brain stimulation of the subthalamic nucleus for essential tremor

查看全文 作　　者：MENG Fan-[1]gang;KAO C. [2]Chris;CHEN [3]Ning;GE [1]Yan;HU Wen-[1]han;ZHANG [3]Kai;[1]MAYu;LIU [1]Chong;ZHANG [1]Xin;ZHANG Jian-[3]guo

机构地区：[1]Beijing Neurosurgical Institute, Capital Medical University,Beijing 100050, China;[2]Department of Neurological Surgery, Vanderbilt UniversityMedical Center, Nashville, TN 37232, USA;[3]Department of Neurosurgery, Beijing Tiantan Hospital, CapitalMedical University, Beijing 100050, China

出　　处：《Chinese Medical Journal》索引2013年第2期,共2页

基　　金：This work was supported partly by the Beijing Health System Advanced Health Technology Talent Cultivation Plan, China (No. 2011-3-032) and the National Natural Science Foundation of China (No. 81071224). 摘　　要：Essential tremor (ET),characterized by a postural and/or kinetic tremor and primarily manifested in the upper extremities,head,and other parts of the body,is one of the most common neurological disorders.1 The traditional target for the neurosurgical treatment of ET,the ventral intermedius nucleus (Vim) of the thalamus,has confirmed that chronic deep brain stimulation (DBS) is an effective,standard,and primary procedure for ET.However,the loss of tremor suppression due to tolerance of chronic Vim stimulation,accompanied by other adverse effects,such as paresthesias,dysarthria,dysequilibrium,hyperhidrosis,and localized pain,has necessitated changes in the stimulation target in some patients.Therefore,an alternative target for ET stimulation is required.Although targeting the subthalamic nucleus (STN) also has complications,such as dyskinesia,dysarthria,paresthesias,diplopia,mood changes,depression,and restless leg syndrome,in view of the evidence that STN could be the target for patients with tremors associated with Parkinson's disease (PD),STN was elected in two ET patients in our study with positive effects.Our research is reported to have explored the possibilities of STN-DBS in the treatment of ET. 关键词：丘脑震颤深部神经系统疾病身体部位外科治疗原发性 VIM

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Deep brain stimulation of the subthalamic nucleus for essential tremor

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