A review on the pharmacological and toxicological aspects of Datura stramonium L.

查看全文 作　　者：Bhakta Prasad [1]Gaire;Lalita [2]Subedi

机构地区：[1]Department of Herbal Pharmacology, College of Oriental Medicine, Kyung Hee University;[2]Department of Pharmaceutical Sciences, School of Health and Allied Sciences, Pokhara University

出　　处：《Journal of Integrative Medicine》索引2013年第11卷第2期,共7页

基　　金：supported by Dr. Katsuko Komatsu Award of Year 2008, Japan 摘　　要：Datura stramonium L., a wild-growing plant of the Solanaceae family, is widely distributed and easily accessible. It contains a variety of toxic tropane alkaloids such as atropine, hyoscamine, and scopolamine. In Eastern medicine, especially in Ayurvedic medicine, D. stramonium has been used for curing various human ailments, including ulcers, wounds, inflammation, rheumatism and gout, sciatica, bruises and swellings, fever, asthma and bronchitis, and toothache. A few previous studies have reported on the pharmacological effects of D. stramonium; however, complete information regarding the pharmacology, toxicity, ethnobotany and phytochemistry remains unclear. Ethnomedicinally, the frequent recreational abuse of D. stramonium has resulted in toxic syndromes. D. stramonium, in the form of paste or solution to relieve the local pain, may not have a deleterious effect; however, oral and systemic administration may lead to severe anticholinergic symptoms. For this reason, it is very important for individuals, mainly young people, to be aware of the toxic nature and potential risks associated with the use of this plant. This comprehensive review of D. stramonium includes information on botany, phytochemistry, pharmacology, toxicology and ethnomedicinal uses. 关键词：药理作用曼陀罗毒理学民族植物学审查茄科植物植物化学坐骨神经痛

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A review on the pharmacological and toxicological aspects of Datura stramonium L.

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引证文献(7)

耦合文献(11)

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