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Pulse Wave Analysis in Patients with Coronary Heart Disease Based on Hilbert-Huang Transformation and Time-domain

查看全文 作  者:LI Fu-[1]feng;WANG Yi-[1]qin;SUN [2]Ren;XUE [3]Song;YAO [1]Di;SHEN Hai-[2]dong 高影响力作者 机构地区:[1]Syndrome Laboratory of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine;[2]Department of Engineering Mechanics, Shanghai Jiao Tong University;[3]Department of Cardio-thoracic Surgery of Renji Hospital Affiliated to Medicine School of Shanghai Jiao Tong University高影响力机构 出  处:《Chinese Journal of Biomedical Engineering(English Edition)》索引2013年第22卷第2期,共8页高影响力期刊 基  金:The National Basic Research Program (973 Program);grant number: 2003CB517108 摘  要:Objective: To study the characteristics of pulse tracings in CHD, and objectively evaluate the significance of pulse signal in diagnosis and appreciation of therapeutic effect in patients with coronary heart disease(CHD), and accordingly provide with theoretic proofs for developing non-invasive technique of pulse diagnosis. Methods: By using the pulse detection system, pulse graphs in CHD patients, patients without CHD and 'health' adults were collected and compared. Then characters of the pulse signal were analyzed with Hilbert-Huang transformation routine (HHT) and time-domain method respectively. Results: There existed characteristic change in pulse graph in CHD. ① h1,h3,h4,h3/h1,t,t5/t4 in time domain parameters of pulse graph increased and w1 was widened. ② 44% of C2 wave in HHT display showed chaotic and disorderly wave and irregularly wave amplitude in CHD. And 72% of C5 Wave exhibited in irregular wave with average wave amplitude over 10 gram-forces. These changes were significantly different from health adults. Conclusion: Characteristic wave of pulse graph extracted with methods of time domain or HHT routine might be considered as proofs for diagnosis and differentiation in CHD. Our researches prognosticate that pulse diagnosis can be used as an ancillary determination in occurrence of CHD for reasons of the advantage of convenient operation and non-invasion. 关 键 词:coronary heart disease(CHD) pulse graph Hilbert-Huang transformation(HHT) time-domain method
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