Histological Subtypes of Lung Cancer in Chinese Males from 2000 to 2012

查看全文 作　　者：ZOU Xiao [1]Nong;LIN Dong [2]Mei;WAN [3]Xia;CHAO [4]Ann;FENG Qin [5]Fu;DAI [1]Zhen;YANG Gong [3]Huan;LV [2]Ning

机构地区：[1]National Office of Cancer Prevention and Control,Cancer Institute/Hospital,Chinese Academy of Medical Sciences;[2]Department of Pathology,Chinese Academy of Medical Sciences;[3]Center for Epidemiology and Biostatistics,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences;[4]Center for Global Health,National Cancer Institute,Bethesda MD,USA;[5]Department of Radiation Oncology,Chinese Academy of Medical Sciences

出　　处：《Biomedical and Environmental Sciences》索引2014年第27卷第1期,共7页

基　　金：supported by NIH Project‘Epidemiology and Intervention Research for Tobacco Control in China’(R01 RFA-TW-06-006);Beijing Run-for-Hope Fund(YF2010-48) 摘　　要：Objective To characterize the histological and epidemiological features of male lung cancer patients in China. Methods The demographic and histological information about male lung cancer patients identified from 2000-01-01 to 2012-12-31,was collected from the Cancer Hospital of the Chinese Academy of Medical Sciences. Relative frequencies(RF) were estimated for major histological subtypes and compared according to the years of diagnosis and birth. Results The RF of adenocarcinoma(ADC) increased from 21.96% to 43.36% and the RF of squamous cell carcinoma(SCC) decreased from 39.11% to 32.23% from 2000 to 2012 in the 15 427 male lung cancer patients included in this study(Z=17.909,P<0.0001; Z=-6.117,P<0.0001). The RF of ADC increased from 28.72% in 2000-2004,36.88% in 2005-2008 to 48.61% in 2009-2012 in patients born after 1960. The age-adjusted RF of ADC in 2007-2012 increased consistently in all the investigated areas. Conclusion The increased RF of ADC in male lung cancer patients highlights the need for further investigation of the etiologic factors of these tumors. Smoke-free policies rather than modifying tobacco products should be enforced. 关键词：中国医学科学院组织学男性肺癌亚型流行病学特征肿瘤医院鳞状细胞癌

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Histological Subtypes of Lung Cancer in Chinese Males from 2000 to 2012

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