Changes in brain functional network connectivity after stroke

查看全文 作　　者：Wei [1,2]Li;Yapeng [1,2]Li;Wenzhen [3]Zhu;Xi [1,2]Chen

机构地区：[1]Key Laboratory of Image Processing and Intelligent Control,Ministry of Education;[2]Department of Control Science and Engineering,Huazhong University of Science and Technology;[3]Department of Radiology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology

出　　处：《Neural Regeneration Research》索引2014年第9卷第1期,共10页

基　　金：supported by the National Natural Science Foundation of China,No.60905024 摘　　要：Studies have shown that functional network connection models can be used to study brain network changes in patients with schizophrenia.In this study,we inferred that these models could also be used to explore functional network connectivity changes in stroke patients.We used independent component analysis to find the motor areas of stroke patients,which is a novel way to determine these areas.In this study,we collected functional magnetic resonance imaging datasets from healthy controls and right-handed stroke patients following their first ever stroke.Using independent component analysis,six spatially independent components highly correlated to the experimental paradigm were extracted.Then,the functional network connectivity of both patients and controls was established to observe the differences between them.The results showed that there were 11 connections in the model in the stroke patients,while there were only four connections in the healthy controls.Further analysis found that some damaged connections may be compensated for by new indirect connections or circuits produced after stroke.These connections may have a direct correlation with the degree of stroke rehabilitation.Our findings suggest that functional network connectivity in stroke patients is more complex than that in healthy controls,and that there is a compensation loop in the functional network following stroke.This implies that functional network reorganization plays a very important role in the process of rehabilitation after stroke. 关键词：网络连接模型中风脑功能独立分量分析功能磁共振成像控制功能精神分裂症独立成分

相关文献

参考文献（60）
引证文献（5）
耦合文献（0）

参考文献(60)

引证文献(5)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Changes in brain functional network connectivity after stroke

参考文献(60)

引证文献(5)

用户提示