Residual activity of cetrimide and chlorhexidine on Enterococcus faecalis-infected root canals

查看全文 作　　者：Carmen María Ferrer-[1]Luque;María Teresa Arias-[2]Moliz;Matilde Ruíz-[1]Linares;María Elena Martínez [1]García;Pilar [1]Baca

机构地区：[1]Department of Stomatology, School of Dentistry, University of Granada;[2]Department of Microbiology, School of Dentistry, University of Granada

出　　处：《International Journal of Oral Science》索引2014年第6卷第1期,共4页

基　　金：supported by the Research Group CTS-167 of the Junta de Andalucí'a, Spain 摘　　要：Effective final irrigation regimen is an important step in order to achieve better disinfection and ensure residual antimicrobial effects after root canal preparation. The aim of this study was to compare the residual antimicrobial activity of 0.2% cetrimide, and 0.2% and 2% chlorhexidine in root canals infected with Enterococcus faecalis. Biofilms of E. faecalis were grown on uniradicular roots for 4 weeks. After root canal preparation, root canals were irrigated with 17% ethylenediaminetetraacetic acid(EDTA) to remove the smear layer. The roots were randomly divided into three experimental groups(n526) according to the final irrigating solution: Group I, 5 mL 0.2% cetrimide; Group II, 5 mL 0.2% chlorhexidine; and Group III, 5 mL 2% chlorhexidine. Samples were collected for 50 days to denote the presence of bacterial growth. The proportion of ungrown specimens over 50 days was evaluated using the nonparametric Kaplan–Meier survival analysis. Differences among groups were tested using the log-rank test and the level of statistical significance was set at P,0.05. The highest survival value was found with 2% chlorhexidine, showing statistically significant differences from the other two groups. At 50 days, E. faecalis growth was detected in 69.23% specimens in Groups I and II, and in 34.61% specimens of Group III. There were no significant differences between 0.2% cetrimide and 0.2% chlorhexidine. Final irrigation with 2% chlorhexidine showed greater residual activity than 0.2% chlorhexidine and 0.2% cetrimide in root canals infected with E. faecalis. 关键词：抗微生物活性粪肠球菌洗必泰根管感染残留铵溴

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Residual activity of cetrimide and chlorhexidine on Enterococcus faecalis-infected root canals

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