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Accumulation and Elimination Kinetics of 2-Methylisoborneol in Crucian Carp (Carassius carassius)

查看全文 作  者:YANG [1]Meng;HU [1]Jiaming;LIU [1]Liming;SHI [1]Xiaotao;LIU [1]Guoyong;ZUO [2]Yanxia 高影响力作者 机构地区:[1]Hubei International Scientific and Technological Cooperation Center of Ecological Conservation and Management in Three Gorges Area;[2]State Key Laboratory of Freshwater Ecology and Biotechnology,Institute of Hydrobiology,Chinese Academy of Sciences高影响力机构 出  处:《Wuhan University Journal of Natural Sciences》索引2019年第24卷第1期,共7页高影响力期刊 基  金:Supported by the National Natural Science Foundation of China(31472293,51179096) 摘  要:2-methylisoborneol(2-MIB) is a common, earthysmelling compound that causes taste and odor issues in aquaculture. To quantify the distribution, absorption, and depuration of 2-MIB in crucian carp(Carassius carassius), we detected and measured 2-MIB it via microwave, headspace solid-phase microextraction(HS-SPME), and gas chromatography before and after exposing fish to two different concentrations of 2-MIB(200 ng/L and 500 ng/L). The results showed that during the exposure time, the fish absorbed 2-MIB rapidly within 4 h. After exposure to 2-MIB for 120 h, the 2-MIB in gill and liver were rapidly removed. The processes of accumulation and elimination of 2-MIB in fish were investigated using the one-compartment kinetic model. The modeling results showed that the range of the uptake rate constant(k1) was 0.49-6.91. The range of the elimination rate constant(k2) was 0.05-0.27 and uptake rates were higher than elimination rates. The bioconcentration factor(BCF) was estimated according to the physicochemical properties of 2-MIB, and the bioaccumulation of 2-MIB in fish had a close correlation with the octanol/water partition coefficient(Kow). 关 键 词:earthy-musty ODOR BIOACCUMULATION ELIMINATION 2-methylisoborneol(2-MIB) fish
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