Electroacupuncture attenuates neuropathic pain after brachial plexus injury

查看全文 作　　者：Shenyu [1,2,3]Zhang;Hailiang [4]Tang;Junming [1,2,3]Zhou;Yudong [1,2,3]Gu

机构地区：[1]Department of Hand Surgery,Huashan Hospital,Fudan University;[2]Key Laboratory of Hand Reconstruction,Ministry of Health;[3]Shanghai Key Laboratory of Peripheral Nerve and Microsurgery;[4]Department of Neurosurgery,Huashan Hospital,Fudan University

出　　处：《Neural Regeneration Research》索引2014年第9卷第14期,共6页

基　　金：supported by the Project of Ministry of Health(Comprehensive Research on Brachial Plexus Injury),No.13D22270800 from the National Natural Science Foundation of China;2011 Shanghai Medical College Young Scientist Fund of Fudan University,No.11L-24 摘　　要：Electroacupuncture has traditionally been used to treat pain, but its effect on pain following brachial plexus injury is still unknown. In this study, rat models of an avulsion injury to the left brachial plexus root(associated with upper-limb chronic neuropathic pain) were given electroacupuncture stimulation at bilateral Quchi(LI11), Hegu(LI04), Zusanli(ST36) and Yanglingquan(GB34). After electroacupuncture therapy, chronic neuropathic pain in the rats' upper limbs was significantly attenuated. Immunofluorescence staining showed that the expression of β-endorphins in the arcuate nucleus was significantly increased after therapy. Thus, experimental findings indicate that electroacupuncture can attenuate neuropathic pain after brachial plexus injury through upregulating β-endorphin expression. 关键词：神经损伤疼痛电针治疗免疫荧光染色大鼠模型内啡肽电刺激病理性

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Electroacupuncture attenuates neuropathic pain after brachial plexus injury

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