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Distribution and drug resistance of pathogenic bacteria isolated from cancer hospital in 2013

查看全文 作  者:Linjuan [1]Liu;Qi [1]Li;Qingyun [1]Zhang;Guohong [1]Wang;Guobin [1]Xu;Ji [2]Zhang 高影响力作者 机构地区:[1]Department of Laboratory, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute;[2]Department of Infection Management, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute高影响力机构 出  处:《Chinese Journal of Cancer Research》索引2014年第26卷第6期,共7页高影响力期刊 摘  要:Objective: To understand distribution and drug resistance of pathogenic bacteria from a specialized cancer hospital in 2013 in order to provide a basis for rational clinical antimicrobial agents. Methods: Pathogenic bacteria identification and drug sensitivity tests were performed with a VITEK 2 compact automatic identification system and data were analyzed using WHONET5.6 software.Results: Of the 1,378 strains tested, 980 were Gram-negative bacilli, accounting for 71.1%, in which Klebsiella pneumonia, Escherichia coli and Pseudomonas aeruginosa were the dominant strains. We found 328 Gram-positive coccus, accounting for 23.8%, in which the amount of Staphylococcus aureus was the highest. We identified 46 fungi, accounting for 4.1%. According to the departmental distribution within the hospital, the surgical departments isolated the major strains, accounting for 49.7%. According to disease types, lung cancer, intestinal cancer and esophagus cancer were the top three, accounting for 20.9%, 17.3% and 14.2%, respectively. No strains were resistant to imipenem, ertapenem or vancomycin.Conclusions: Pathogenic bacteria isolated from the specialized cancer hospital have different resistance rates compared to commonly used antimicrobial agents; therefore antimicrobial agents to reduce the morbidity and mortality of infections should be used. 关 键 词:病原菌分离 肿瘤医院 耐药性 金黄色葡萄球菌 自动识别系统 革兰阴性杆菌 铜绿假单胞菌 抗菌药物
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