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Alcohol liver disease: A review of current therapeutic approaches to achieve long-term abstinence

查看全文 作  者:María Luisa Gutiérrez [1]García;Sara Blasco-[1]Algora;Conrado M Fernández-[1]Rodríguez 高影响力作者 机构地区:[1]Service of Gastroenterology,Hospital Universitario Fundación高影响力机构 出  处:《World Journal of Gastroenterology》索引2015年第21卷第28期,共11页高影响力期刊 摘  要:Harmful alcohol drinking may lead to significant damage on any organ or system of the body.Alcoholic liver disease(ALD) is the most prevalent cause of advanced liver disease in Europe.In ALD,only alcohol abstinence was associated with a better long-term survival.Therefore,current effective therapeutic strategy should be oriented towards achieving alcohol abstinence or a significant reduction in alcohol consumption.Screening all primary care patients to detect those cases with alcohol abuse has been proposed as population-wide preventive intervention in primary care.It has been suggested that in patients with mild alcohol use disorder the best approach is brief intervention in the primary care setting with the ultimate goal being abstinence,whereas patients with moderate-to-severe alcohol use disorder must be referred to specialized care where detoxification and medical treatment of alcohol dependence must be undertaken. 关 键 词:ALCOHOL use DISORDERS ALCOHOLIC liver disease ALCOHOL ABSTINENCE ALCOHOL WITHDRAWAL syndrome ALCOHOL DEPENDENCE
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