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Esophageal stenosis with sloughing esophagitis:A curious manifestation of graft-vs-host disease

查看全文 作  者:Daniel [1]Trabulo;Sara [2]Ferreira;Pedro [2]Lage;Rafaela Lima [3]Rego;Gilda [4]Teixeira;A Dias [2]Pereira 高影响力作者 机构地区:[1]Gastroenterology Department,Hospital de S?o Bernardo,Centro Hospitalar de Setúbal E.P.E.,2910-446 Setúbal,Portugal;[2]Gastroenterology Department,Instituto Português de Oncologia de Lisboa de Francisco Gentil;[3]Pathology Department,Instituto Português de Oncologia de Lisboa de Francisco Gentil;[4]Hemathology Department,Instituto Português de Oncologia de Lisboa de Francisco Gentil高影响力机构 出  处:《World Journal of Gastroenterology》索引2015年第21卷第30期,共6页高影响力期刊 摘  要:We report a case of a 56-year-old woman with a history of allogenic bone marrow transplantation for two years,complaining with dysphagia and weight loss. Upper endoscopy revealed esophageal stenosis and extensive mucosa sloughing. Biopsies confirmed the diagnosis of graft-vs-host disease(GVHD). Balloon dilation,corticosteroids and cyclosporin resulted in marked clinical improvement. Gastrointestinal tract is involved in the majority of patients with chronic GVHD. Esophageal manifestations are rare and include vesiculobullous disease,ulceration,esophageal webs,casts or strictures. Sloughing esophagitis along with severe stenosis requiring endoscopic dilation has never been reported in this context. 关 键 词:DYSPHAGIA Esophageal STENOSIS Sloughingesophagitis BALLOON DILATION Graft-vs -host-disease
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