Traditional Chinese medicine for prevention and treatment of hepatocarcinoma: From bench to bedside

查看全文 作　　者：Bing [1]Hu;Shuang-Shuang [1]Wang;Qin [1]Du

机构地区：[1]Department of Oncology and Institute of Traditional Chinese Medicine in Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine

出　　处：《World Journal of Hepatology》索引2015年第7卷第9期,共24页

基　　金：National Natural Science Foundation of China,Nos.81273726 and 81473625;Three-year Action Program of Shanghai Municipality for Traditional Chinese Medicine,No.ZY3-CCCX-3-3025 摘　　要：Traditional Chinese medicine(TCM) has played a positive role in the management of hepatocarcinoma. Hepatocarcinoma patients may present Qi-stagnation, damp-heat, blood stasis, Qi-deficiency, Yin-deficiency and other TCM syndromes(Zheng). Modern treatments such as surgery, transarterial chemoembolization(TACE) and high intensity focus ultrasound treatment would influence the manifestation of TCM syndromes. Herbs with traditional efficacy of tonifying Qi, blood and Yin, soothing liver-Qi stagnation, clearing heat and detoxifying and dissolving stasis, have been demonstrated to be potent to prevent hepatocarcinogenesis. TCM has been widely used in all aspects of integrative therapy in hepatocarcinoma, including surgical resection, liver transplantation, TACE, local ablative therapies and even as monotherapy for middle-advanced stage hepatocarcinoma. Clinical practices have confirmed that TCM is effective to alleviate clinical symptoms, improve quality of life and immune function, prevent recurrence and metastasis, delay tumor progression, and prolong survival time in hepatocarcinoma patients. The effective mechanism of TCM against hepatocarcinoma is related to inducing apoptosis, autophagy, anoikis and cell senescence, arresting cell cycle, regulating immune function, inhibiting metastasis and angiogenesis, reversing drug resistance and enhancing effects of chemotherapy. Along with the progress of research in this field, TCM will contribute more to the prevention and treatment of hepatocarcinoma. 关键词：HEPATOCARCINOMA TRADITIONAL Chinesemedicine Prevention Treatment TRADITIONAL Chinesemedicine syndrome (Zheng) Therapeutic principle CHINESE herbal formula CHINESE HERB

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Traditional Chinese medicine for prevention and treatment of hepatocarcinoma: From bench to bedside

参考文献(205)

引证文献(23)

耦合文献(1573)

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