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Comparison of Snellen and Early Treatment Diabetic Retinopathy Study charts using a computer simulation

查看全文 作　　者：Reuben [1]R.Shamir;Yael [2]Friedman;Leo [1]Joskowicz;Michael [3]Mimouni;Eytan [3]Z.Blumenthal 高影响力作者 机构地区：[1]School of Engineering and Computer Science, the Hebrew University;[2]Department of Ophthalmology, Hadassah-Hebrew University Medical Center;[3]Department of Ophthalmology, Rambam Medical Center高影响力机构 出　　处：《International Journal of Ophthalmology(English edition)》索引2016年第9卷第1期,共5页高影响力期刊 摘　　要：AIM:To compare accuracy,reproducibility and test duration for the Snellen and the Early Treatment Diabetic Retinopathy Study(ETDRS)charts,two main tools used to measure visual acuity(VA).·METHODS:A computer simulation was programmed to run multiple virtual patients,each with a unique set of assigned parameters,including VA,false-positive and false-negative error values.For each virtual patient,assigned VA was randomly chosen along a continuous scale spanning the range between 1.0 to 0.0 log MAR units(equivalent to 20/200 to 20/20).Each of 30 000virtual patients were run ten times on each of the two VA charts.·RESULTS:Average test duration(expressed as the total number of characters presented during the test±SD)was12.6±11.1 and 31.2±14.7 characters,for the Snellen and ETDRS,respectively.Accuracy,defined as the absolute difference(±SD)between the assigned VA and the measured VA,expressed in log MAR units,was superior in the ETDRS charts:0.12±0.14 and 0.08±0.08,for the Snellen and ETDRS charts,respectively.Reproducibility,expressed as test-retest variability,was superior in the ETDRS charts:0.23±0.17 and 0.11±0.09 log MAR units,for the Snellen and ETDRS charts,respectively.·CONCLUSION:A comparison of true(assigned)VA to measured VA,demonstrated,on average,better accuracy and reproducibility of the ETDRS chart,but at the penalty of significantly longer test duration.These differences were most pronounced in the low VA range.The reproducibility using a simulation approach is in line with reproducibility values found in several clinical studies. 关 键 词：早治疗糖尿病的 Retinopathy 学习 Snellen 计算机模拟 测试的视觉尖酸 虚拟病人
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