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Inflammatory bowel disease associated neoplasia:Asurgeon's perspective

查看全文 作  者:Azah A [1]Althumairi;Mark G [2]Lazarev;Susan L [1]Gearhart 高影响力作者 机构地区:[1]Division of Colorectal Surgery,Department of Surgery,Johns Hopkins University School of Medicine,Baltimore,MD 21287,United States;[2]Division of Gastroenterology,Department of Medicine,Johns Hopkins University School of Medicine,Baltimore,MD 21287,United States高影响力机构 出  处:《World Journal of Gastroenterology》索引2016年第22卷第3期,共13页高影响力期刊 摘  要:Inflammatory bowel disease(IBD) is associated with increased risk of colorectal cancer(CRC). The risk is known to increase with longer duration of the disease, family history of CRC, and history of primary sclerosing cholangitis. The diagnosis of the neoplastic changes associated with IBD is difficult owing to the heterogeneous endoscopic appearance and interobserver variability of the pathological diagnosis. Screening and surveillance guidelines have been established which aim for early detection of neoplasia. Several surgical options are available for the treatment of IBD-associated neoplasia. Patients' morbidities, risk factors for CRC, degree and the extent of neoplasia must be considered in choosing the surgical treatment. A multidisciplinary team including the surgeon, gastroenterologist, pathologist, and the patient who has a clear understanding of the nature of their disease is needed to optimize outcomes. 关 键 词:Inflammatory BOWEL disease DYSPLASIA COLORECTAL cancer ENDOSCOPY Surveillance COLECTOMY
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