Anal cancer and intraepithelial neoplasia screening: A review

查看全文 作　　者：Ira L [1]Leeds;Sandy H [1]Fang

机构地区：[1]Ravitch Division,Colon and Rectal Surgery, Department of Surgery, Johns Hopkins Hospital

出　　处：《World Journal of Gastrointestinal Surgery》索引2016年第8卷第1期,共11页

摘　　要：This review focuses on the early diagnosis of anal cancerand its precursor lesions through routine screening. A number of risk-stratification strategies as well as screening techniques have been suggested, and currently little consensus exists among national societies. Much of the current clinical rationale for the prevention of anal cancer derives from the similar tumor biology of cervical cancer and the successful use of routine screening to identify cervical cancer and its precursors early in the disease process. It is thought that such a strategy of identifying early anal intraepithelial neoplasia will reduce the incidence of invasive anal cancer. The low prevalence of anal cancer in the general population prevents the use of routine screening. However, routine screening of selected populations has been shown to be a more promising strategy. Potential screening modalities include digital anorectal exam, anal Papanicolaou testing, human papilloma virus co-testing, and high-resolution anoscopy. Additional research associating high-grade dysplasia treatment with anal cancer prevention as well as direct comparisons of screening regimens is necessary to develop further anal cancer screening recommendations. 关键词：ANAL cancer SECONDARY PREVENTION AnalPapanicolaou test HIGH-RESOLUTION anoscopy SCREENING

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Anal cancer and intraepithelial neoplasia screening: A review

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