Recent advances in synthetic carbohydrate-based human immunodeficiency virus vaccines

查看全文 作　　者：Zhenyuan [1]Wang;Chunjun [1]Qin;Jing [1,2]Hu;Xiaoqiang [1]Guo;Jian [1]Yin

机构地区：[1]Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of Education, School of Biotechnology, Jiangnan University;[2]Wuxi Medical School, Jiangnan University

出　　处：《Virologica Sinica》索引2016年第31卷第2期,共8页

基　　金：the National Science Foundation for Young Scientists of China(No.21302068);the Natural Science Foundation of Jiangsu Province,China(No.BK20130127,BK20140154,and BK20150140);the Public Health Research Center at Jiangnan University(No.JUPH201502);Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of Education,Jiangnan University(KLCCB-KF201504) 摘　　要：An effective vaccine for human immunodeficiency virus(HIV) is urgently needed to prevent HIV infection and progression to acquired immune deficiency syndrome(AIDS). As glycosylation of viral proteins becomes better understood, carbohydrate-based antiviral vaccines against special viruses have attracted much attention. Significant efforts in carbohydrate synthesis and immunogenicity research have resulted in the development of multiple carbohydrate-based HIV vaccines. This review summarizes recent advances in synthetic carbohydrate-based vaccines design strategies and the applications of these vaccines in the prevention of HIV. 关键词：人类免疫缺陷病毒抗病毒疫苗碳水化合物基础合成艾滋病毒病毒感染病毒蛋白

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Recent advances in synthetic carbohydrate-based human immunodeficiency virus vaccines

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