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Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease

查看全文 作  者:Xia [1,2]Chen;Kailin [3]Yang;Chen [1]Wu;Cheng [1]Chen;Can [1,2]Hu;Olga [4]Buzovetsky;Zefang [1]Wang;Xiaoyun [5]Ji;Yong [4]Xiong;Haitao [1,2]Yang 高影响力作者 机构地区:[1]School of Life Sciences, Tianjin University, Tianjin 300072, China;[2]Tianjin International Joint Academy of Biotechnology and Medicine, Tianjin 300457, China;[3]Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA;[4]Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA;[5]The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China高影响力机构 出  处:《Cell Research》索引2016年第26卷第11期,共4页高影响力期刊 基  金:We would like to thank Zuokun Lu for data collection at beam-line BL 18U 1 of the Shanghai Synchrotron Radiation Facility (SSRF); Jingshan Ren and Lanfeng Wang for discussion and advice; Yusheng Tan, Haofeng Wang, Zhengbao Xia and Jinxin Hu for technical support. This work was supported by National Key Basic Research Program of China (973 program) (2015CB859800), National Key Research Program of China (2016YFD0500300), and National Natural Science Foundation of China (31528006 and 31470730). 关 键 词:抑制机制 蛋白酶 病毒 激活
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