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BMI and BMI Changes to All-cause Mortality among the Elderly in Beijing: a 20-year Cohort Study

查看全文 作  者:WANG Yun [1,2]Feng;TANG [3]Zhe;GUO [1,2]Jin;TAO Li [1,2]Xin;LIU [1,2]Long;LI Hai [1,2]Bin;LI Di [4]Tian;GUO Xiu [1,2]Hua;YANG Xing [1,2]Hua 高影响力作者 机构地区:[1]School of Public Health, Capital Medical University, Beijing 100069, China;[2]Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing 100069, China;[3]School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China;[4]School of Basic Medical Sciences, Peking University Health Science Center, Beijing100191, China高影响力机构 出  处:《Biomedical and Environmental Sciences》索引2017年第30卷第2期,共9页高影响力期刊 基  金:supported by the Beijing Natural Science Foundation(7131002);the Key Projects in the National Science&Technology Pillar Program in the Twelfth Five-year Plan Period of China(2011BAI08B01);the Beijing Municipal Natural Science Foundation(Serial Number:7122016) 摘  要:Objective To explore the association between body mass index(BMI)and all-cause mortality among the elderly in Beijing.Methods This analysis was based on the Beijing multidimensional longitudinal study of aging(BLSA),which included 2,090 subjects over 55 years old and was followed-up from 1992 to 2012.BMI-mortality curves were drawn to find the optimal BMI range with the lowest mortality.Cox proportional hazard models were used to obtain the hazard ratios(HRs)for BMI and BMI changes in the overall population and in specific stratified populations.Results During follow-up,1,164 deaths were recorded;BMI-mortality curve was U-shaped,with the lowest mortality at a BMI of approximately 25 kg/m^2.After adjusting for gender,age,smoking,drinking and some pre-existing diseases,HRs for underweight,overweight and obesity compared with normal weight were 1.372(95%CI:1.154-1.631),0.767(95%CI:0.666-0.884)and 0.871(95%CI:0.830-1.246),respectively.HR for BMI drop was 3.245(95%CI:0.824-12.772)in the underweight group and 1.892(95%CI:0.830-1.246)in the normal weight group,HR for BMI rise was 1.795(95%CI:1.243-2.591)in normal weight group and 1.962(95%CI:1.202-3.203)in the overweight group.Conclusion Keeping BMI in an overweight status and stable is related to a reduced mortality. 关 键 词:身体集体索引 所有原因死亡 北京
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