Isatin hybrids and their anti-tuberculosis activity

查看全文 作　　者：Zhi [1]Xu;Shu [2]Zhang;Chuan [3]Gao;Jing [4]Fan;Feng [3]Zhao;Zao-Sheng [1]Lv;Lian-Shun [1,3,5]Feng

机构地区：[1]Wuhan University of Science and Technology, 430081, China;[2]Pony Testing International Group, Wuhan 430034, China;[3]WuXi AppTec, Wuhan 430075, China;[4]Hengshui University, Hengshui 053000, China;[5]Synthetic and Functional Biomolecules Center, Peking University, Beijing 100871, China

出　　处：《Chinese Chemical Letters》索引2017年第28卷第2期,共9页

摘　　要：Tuberculosis(TB) is one of the most common and even fatal infectious diseases known to mankind.Millions of new cases are reported every year over the world,and one-third of the world's population is potentially infected with mycobacteria tuberculosis(MTB).Research to develop novel anti-TB drugs led to the identification of several isatin-based antimycobacterial agents,among which a number of potential candidates displayed excellent antimycobacterial activity and were found to be free of cytotoxicity.This review outlines the advances in the application of isatin hybrids as antimycobacterial agents and the critical aspects of design and structure-activity relationship of these derivatives. 关键词：靛红混血儿 Mycobacterium 肺结核 QUINOLONE 结构活动关系评论

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Isatin hybrids and their anti-tuberculosis activity

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引证文献(11)

耦合文献(9)

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