Organ-specific alterations in circadian genes by vertical sleeve gastrectomy in an obese diabetic mouse model

查看全文 作　　者：Qiwei [1]Shen;Yeping [2]Yang;Wenjuan [2]Liu;Meng [2]Wang;Yikai [1]Shao;Bo [1]Xu;Xiaolong [2]Zhao;Jinxing [3]Zhu;Rong [1]Hua;Wanzhu [4]Jin;Zhiyu [5]Hu;Jae Bum [6]Kim;Qinghua [2,8]Wang;Yiming [2,8]Li;Mengwei [7]Zang;Qiyuan [1]Yao;Zhaoyun [2,8]Zhang 机构地区：[1]Center for Obesity and Metabolic Surgery, Department of General Surgery, Huashan Hospital, Fudan University, Shanghai 200040, China;[2]Division of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China;[3]Department of Pathology, Huashan Hospital, Fudan University, Shanghai 200040, China;[4]Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;[5]National Key Laboratory of Sdence and Technology on Micro/Nano Fabrication, Shanghai Jiao Tong University, Shanghai 200240, China;[6]National Creative Research Initiatives Center for Adipose Tissue Remodeling, Department of Biological Sciences, Institute of Molecular Biology and Genetics, Seoul National University, Seoul 08826, South Korea;[7]Department of Medicine, Whituker Cardiovascular Institute, Boston University School of Medicine, Boston 02215, USA;[8]Institute of Endocrinology and Diabetology, Fudan University, Shanghai 200040, China 出　　处：《Science Bulletin》索引2017年第62卷第7期,共3页 基　　金：supported by the National Natural Science Foundation of China(81370938);Shanghai Municipal Commission of Health and Family Planning(XYQ2011002);Shanghai Science and Technology Committee(11PJ1402000);Shenkang Hospital Development Center(SHDC12012220);the ‘‘Strategic Priority Research Program” of the Chinese Academy of Science(XDB13030500) 摘　　要：Current therapies for obesity and related complications have been shown to have limited benefits,including unsatisfactory weight loss and poor metabolic improvement.With recent developments in bariatric surgery,promising advancements have been made in clinical and scientific research,particularly in the management of obesity and diabetes.Vertical sleeve gastrectomy(VSG)has become increasingly popular due to its safety,simplicity, 关 键 词：VSG In Organ-specific alterations in circadian genes by vertical sleeve gastrectomy in an obese diabetic mouse model WAT PGC