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ADMETNet:The knowledge base of pharmacokinetics and toxicology network

查看全文 作  者:Quan [1]Xu;Ke [1]Liu;Xingming [1]Lin;Yangmei [1]Qin;Linshan [1]Chen;Jiao [1]Cheng;Mindong [1]Zhong;Qiushun [1]He;Yinbo [1]Li;Tingwu [1]Wang;Jianbo [1]Pan;Menglu [1]Peng;Lixia [2]Yao;Zhiliang [1,3]Ji 高影响力作者 机构地区:[1]State Key Laboratory of Stress Cell Biology,School of Life Sciences,Xiamen University,Xiamen 361102,China;[2]Department of Health Sciences Research,Mayo Clinic,Rochester,MN 55905,USA;[3]The Key Laboratory,0r Chemical Biology of Fujian Province,Xiamen University,Xiamen 361005,China高影响力机构 出  处:《Journal of Genetics and Genomics》索引2017年第44卷第5期,共4页高影响力期刊 基  金:supported by the Natural Science Foundation ofChina(Nos.30873159 and 31271405) 摘  要:A good drug or drug candidate should not only interact with its target molecule effectively and specifically,but also be absorbed into the body,distributed to the right location,metabolized into right compounds,and eliminated out of the body in proper manner.The processes of drug getting into and out of the body involve Absorption,Distribution,Metabolism,and Excretion(ADME),which 关 键 词:药代动力学 毒理学 知识库 网络 人体吸收 目标分子 药物 化合物
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