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Prescriptions from Traditional Chinese Medicine compared with salbutamol and montelukast for the treatment of pediatric asthma: a randomized controlled trial

查看全文 作　　者：Du [1]Hui;Wang [1]Yonghong;Yu [1]Jian;Shi [1]Yumin;Li [1]Suhuan;Sun [1]Wen;Zhang [1]Yiqun;Hu [1]Hong 高影响力作者 机构地区：[1]Department of Traditional Chinese Medicine, Children's Hospital of Fudan University, Shanghai 201102, China高影响力机构 出　　处：《Journal of Traditional Chinese Medicine》索引2017年第37卷第4期,共8页高影响力期刊 基　　金：Supported by a Major Research Project of Shanghai Traditional Chinese Medicine Three-year Action Plan(No.ZYSNXD-CC-ZDYJ034);Shanghai Science and Technology Research Program(No.12401905500);a Development Project of Shanghai Peak Disciplines-Integrated Chinese and Western Medicine(No.20150407) 摘　　要：OBJECTIVE: To compare the effects of a series of Traditional Chinese Medicine(TCM) empirical prescriptions with salbutamol and montelukast(SM) in children with asthma.METHODS: A total of 182 children with asthma were randomized into the TCM group(n = 97) or SM group(n = 85). Patients in the TCM group were treated with a series of TCM prescriptions, whereas those in the SM group received salbutamol and montelukast; both groups received their respective treatment for 12 weeks. Asthma control, changes in scores of TCM symptom patterns, and asthma symptom control(SC) scores after treatment were compared between the two groups.RESULTS: A higher percentage of patients in the TCM group had asthma control compared withthose in the SM group(91.67% and 76.83%, respectively, P = 0.006). Scores for abnormal feces(P <0.001), hyperhidrosis(P < 0.001), and tongue appearance(P = 0.001) in the TCM group were significantly better than those in the SM group. However,the total scores of TCM symptom patterns and SC scores did not differ significantly between the two groups(P > 0.05).CONCLUSION: Compared with salbutamol and montelukast, the TCM prescriptions tested were better for symptom control in children with asthma. 关 键 词：气喘 ALBUTEROL 排汇物 剧汗 反常舌头演讲 症候群区别 中国医药公式 使随机化的控制审判
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