Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis

查看全文 作　　者：Lin [1]He;Xinhua [1,2,3]Liu;Jianguo [1]Yang;Wanjin [1]Li;Shumeng [2]Liu;Xujun [1]Liu;Ziran [1]Yang;Jie [1]Ren;Yue [2]Wang;Lin [2]Shan;Chengjian [4]Guan;Fei [5]Pei;Liandi [6]Lei;Yu [1]Zhang;Xia [1]Yi;Xiaohan [1]Yang;Jing [1]Liang;Rong [4]Liu;Luyang [1]Sun;Yongfeng [1,2,3]Shang

机构地区：[1]Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China;[2]Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China;[3]Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China;[4]Department of Hepatoblliary and Pancreatic Surgical Oncology, Chinese People's Liberation Army General Hospital, Beijing 1 00853, China;[5]Department of Pathology, Schoo) of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China;[6]Laboratory of Molecular Imaging, Peking University Health Science Center, Beijing 100191, China

出　　处：《Cell Research》索引2018年第28卷第9期,共18页

基　　金：This work was supported by grants (91219201 and 81530073 to Y.S., and 81372223, 81422034 and 31571340 to L.S.) from the National Natural Science Foundation of China, and grants (2016YFC1302304 to Y.S. and 2014CB542004 to L.S.) from the Ministry of Science and Technology of China. 关键词：不平衡驱动器循环酶 EGFR 细胞质 VIVO AKT

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Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis

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