SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation

查看全文 作　　者：Yanpeng [1,2]Ci;Xiaoning [2,3]Li;Maorong [4]Chen;Jiateng [2,5]Zhong;Brian J. [2]North;Hiroyuki [2,6]Inuzuka;Xi [4]He;Yu [1]Li;Jianping [2]Guo;Xiangpeng [2]Dai

机构地区：[1]School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China;[2]Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA;[3]Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan 030001, China;[4]The FM Kirby Neurobiology Center, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA;[5]Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China;[6]Center for Advanced Stem Cell and Regenerative Research, Tohoku University Graduate School of Dentistry,Sendai 980-8575, Japan

出　　处：《Protein & Cell》索引2018年第9卷第10期,共11页

基　　金：We thank Dr. W. Wei as well as the He and Wei lab members for critical discussion and reading of the manuscript. X. Ci received financial supporc from the China Scholarship Council (CSC) (No.201606120241). X. Dai is supported by National Research Service Award T-32 training grant. This work was partly supported by the National Natural Science Foundation of China No. 31571323 to Y. Li. X. He acknowledges support by NIH (RO1-GM057603) and by Boston Children's Hospital Intellectual and Developmental Disabili- ties Research Center (P30 HD-18655). X. He is an American Cancer Society Research Professor. 关键词：SCF 指向肿瘤 WNT 管理者织物开发织物类型调查结果

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SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation

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