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How botulinum toxin in neurogenic detrusor overactivity can reduce upper urinary tract damage?

查看全文 作  者:Maximilien [1]Baron;Philippe [1]Grise;Jean-Nicolas [1]Cornu 高影响力作者 机构地区:[1]Department of Urology, Rouen University Hospital高影响力机构 出  处:《World Journal of Nephrology》索引2016年第5卷第2期,共9页高影响力期刊 摘  要:Intradetrusor injections of botulinum toxin are the cornerstone of medical treatment of neurogenic detrusor overactivity. The primary aim of this treatment is to ensure a low pressure regimen in the urinary bladder, but the mechanisms leading to long-term protection of the urinary tract remain poorly understood. In this paper, we highlight the potential benefits of intradetrusor injections of botulinum toxin regarding local effects on the bladder structures, urinary tract infections, stone disease, vesico ureteral reflux, hydronephrosis, renal function based on a comprehensive literature review. 关 键 词:肉毒杆菌 毒性 结石病 治疗方法
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