Syphilis testing algorithms:A review

查看全文 作　　者：Steven R [1]Binder;Elitza S [2]Theel

机构地区：[1]Clinical Diagnostic Group,Bio-Rad Laboratories;[2]Department of Laboratory Medicine and Pathology,Mayo Clinic

出　　处：《World Journal of Immunology》索引2016年第6卷第1期,共8页

摘　　要：The methods and strategies used to screen for syphilis and to confirm initially reactive results can vary significantly across clinical laboratories.While the performance characteristics of these different approaches have been evaluated by multiple studies,there is not,as of yet,a single,universally recommende dalgorithm for syphilis testing.To clarify the currently available options for syphilis testing,this update will summarize the clinical challenges to diagnosis,review the specific performance characteristics of treponemal and non-treponemal tests,and finally,summarize select studies published over the past decade which have evaluated these approaches.Specifically,this review will discuss the traditional and reverse sequence syphilis screening algorithms commonly used in the United States,alongside a discussion of the European Centre for Disease Prevention and Control syphilis algorithm.Ultimately,in the United States,the decision of which algorithm to use is largely dependent on laboratory resources,the local incidence of syphilis and patient demographics. 关键词：SYPHILIS Treponemal infection IMMUNOASSAY Reverse sequence screening Rapid plasma regain Treponema pallidum particle agglutination test AUTOMATION Algorithm Primary infection Late latent infection

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Syphilis testing algorithms:A review

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