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The use of a standardized Chinese herbal formula in patients with advanced lung cancer:a feasibility study

查看全文 作　　者：Goulnar [1]Kasymjanova;Anh-Thi [1]Tran;Victor [1]Cohen;Carmela [1]Pepe;Lama [1]Sakr;David [1]Small;Jason Scott [1]Agulnik;Robert Thomas [1]Jagoe 高影响力作者 机构地区：[1]Peter Brojde Lung Cancer Center, Segal Cancer Center, Jewish General Hospital高影响力机构 出　　处：《Journal of Integrative Medicine》索引2018年第16卷第6期,共6页高影响力期刊 摘　　要：Objective: Increasing numbers of cancer patients are using Chinese herbs(CHs). However, differences among prior studies make it difficult to draw firm conclusions about the clinical usefulness of any specific CH formula. The primary objective of this study was to establish the acceptability of taking a standardized CH formula for patients with advanced lung cancer. The secondary objective was to identify any toxicities attributable to this CH formula and to measure changes in quality of life.Methods: A single-arm, prospective study of a 6-week intervention with a selected CH formula in15 patients with stage 4 nonsmall-cell lung cancer(NSCLC, Seventh American Joint Committee on Cancer TNM staging system).Results: Patients with advanced lung cancer were interested in using the CH formula. Completion(93%)and adherence(98%) levels were very high and most patients perceived the CH treatment as easy to take and were willing to take the CHs used in the study again if it was available. About half of the patients reported adverse events, all of which were mild(Grade 1 or 2) and only a small minority(8%) were potentially related to CHs. No biochemical or hematological evidence of toxicity was observed. Overall, there were improvement in quality of life, and reduced feelings of tiredness and sleepiness.Conclusion: This study provides preliminary evidence that short-term use of a carefully selected and prepared CH formula in patients with stage 4 NSCLC is acceptable and safe. 关 键 词：癌症病人 标准化 公式 中国 肺 草药 生物化学 TNM
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