维普中文期刊产品整合服务

Combination of two-hour post-endoscopic retrograde cholangiopancreatography amylase levels and cannulation times is useful for predicting post-endoscopic retrograde cholangiopancreatography pancreatitis

查看全文 作　　者：Shiro [1]Hayashi;Tsutomu [1]Nishida;Hiromi [1]Shimakoshi;Akiyoshi [1]Shimoda;Takahiro [1]Amano;Aya [1]Sugimoto;Kei [1]Takahashi;Kaori [1]Mukai;Tokuhiro [1]Matsubara;Masashi [1]Yamamoto;Sachiko [1]Nakajima;Koji [1]Fukui;Masami [1]Inada 高影响力作者 机构地区：[1]Department of Gastroenterology and Hepatology,Toyonaka Municipal Hospital高影响力机构 出　　处：《World Journal of Gastrointestinal Endoscopy》索引2016年第8卷第20期,共8页高影响力期刊 摘　　要：AIM To estimate the efficacy of 2 h post-endoscopic retrograde cholangiopancreatography(ERCP) serum amylase levels and other factors for predicting postERCP pancreatitis.METHODS This was a retrospective,single-center cohort study of consecutive patients who underwent ERCP from January 2010 to December 2013.Serum amylase levels were measured 2 h post-procedure,and patient- and procedure-related pancreatitis(PEP) risk factors wereanalyzed using a logistic model.RESULTS A total of 1520 cases(average age 72 ± 12 years,60% male) were initially enrolled in this study,and 1403 cases(725 patients) were ultimately analyzed after the exclusion of 117 cases.Fifty-five of these cases developed PEP.We established a 2 h serum amylase cutoff level of two times the upper limit of normal for predicting PEP.Multivariate analysis revealed that a cannulation time of more than 13 min [odds ratio(OR) 2.28,95%CI:1.132-4.651,P=0.0210] and 2 h amylase levels greater than the cutoff level(OR=24.1,95%CI:11.56-57.13,P<0.0001) were significant predictive factors for PEP.Forty-seven of the 55 patients who developed PEP exhibited 2 h amylase levels greater than the cutoff level(85%),and six of the remaining eight patients who developed PEP(75%) required longer cannulation times.Only 2 of the 1403 patients(0.14%) who developed PEP did not exhibit concerning 2 h amylase levels or require longer cannulation times.CONCLUSION These findings indicate that the combination of 2 h post-ERCP serum amylase levels and cannulation times represents a valuable marker for identifying patients at high risk for PEP. 关 键 词：Serum AMYLASE LEVELS CANNULATION time Post-endoscopic retrograde CHOLANGIOPANCREATOGRAPHY PANCREATITIS Predictor
相关文献

参考文献(30)

引证文献(6)

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费