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Secondary endoscopic submucosal dissection for locally recurrent or incompletely resected gastric neoplasms

查看全文 作　　者：Da Hyun [1]Jung;Young Hoon [1]Youn;Jie-Hyun [1]Kim;Jae Jun [1]Park;Hyojin [1]Park 高影响力作者 机构地区：[1]Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine高影响力机构 出　　处：《World Journal of Gastroenterology》索引2018年第24卷第33期,共10页高影响力期刊 基　　金：Supported by Basic Science Research Program through the National Research Foundation of Korea(NRF);funded by the Ministry of Science and ICT(NRF-2015R1C1A1A01054352) 摘　　要：AIM To investigate the feasibility and safety of secondary endoscopic submucosal dissection(ESD) for residual or locally recurrent gastric tumors. METHODS Between 2010 and 2017, 1623 consecutive patients underwent ESD for gastric neoplasms at a single tertiary referral center. Among these, 28 patients underwent secondary ESD for a residual or locally recurrent tumor. Our analysis compared clinicopathologic factors between primary ESD and secondary ESD groups. RESULTS The en bloc resection and curative rate of resection of secondary ESD were 92.9% and 89.3%, respectively. The average procedure time of secondary ESD was significantly longer than primary ESD(78.2 min vs 55.1 min, P = 0.004), and the adverse events rate was not significantly different but trended slightly higher in the secondary ESD group compared to the primary ESD group(10.7% vs 3.8%, P = 0.095). Patients who received secondary ESD had favorable outcomes without severe adverse events. During a mean follow-up period, no local recurrence occurred in patients who received secondary ESD. CONCLUSION Secondary ESD of residual or locally recurrent gastric tumors appears to be a feasible and curative treatment though it requires greater technical efficiency and longer procedure time. 关 键 词：SECONDARY ENDOSCOPIC SUBMUCOSAL DISSECTION ENDOSCOPIC SUBMUCOSAL DISSECTION Gastric neoplasms Residual TUMORS RECURRENT TUMORS
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